DRUG-RESISTANT HYPERTENSION IN PRIMARY ALDOSTERONISM
نویسندگان
چکیده
منابع مشابه
Aldosteronism and Resistant Hypertension
Resistant hypertension (RHTN) is defined as blood pressure (BP) that remains uncontrolled in spite of intake of ≥3 antihypertensive medications, ideally prescribed at optimal doses and one of which is a diuretic. The incidence of primary aldosteronism (PA) in patients with RHTN is estimated in prospective studies to be 14 to 23%, which is higher than in the general hypertensive population. Pati...
متن کاملClinical implications of primary aldosteronism with resistant hypertension.
Twenty-eight patients with resistant hypertension were found to have primary aldosteronism; 25 had solitary adenoma and 3 had adrenal hyperplasia. All were severely hypertensive despite receiving three or more antihypertensive agents, including conventional doses of diuretics, sympatholytics, and vasodilators. Hypervolemia (24 patients) or normovolemia (2 patients) despite severe diastolic hype...
متن کاملProgress in aldosteronism: a review of the prevalence of primary aldosteronism in pre-hypertension and hypertension.
Primary aldosteronism (PA) secondary to excessive and/or autonomous aldosterone secretion from the renin-angiotensin system accounts for ∼10% of cases of hypertension and is primarily caused by bilateral adrenal hyperplasia (BAH) or aldosterone-producing adenomas (APAs). Although the diagnosis has traditionally been supported by low serum potassium levels, normokalaemic and even normotensive fo...
متن کاملEvolution of diagnostic criteria for primary aldosteronism: why is it more common in "drug-resistant" hypertension today?
The recent "epidemic" of primary aldosteronism reported in the literature is most likely related to the widespread acceptance that with easy access to accurate measurements of renin and aldosterone, it is no longer necessary to wait until hypokalemia has become profound before embarking on diagnostic testing to attempt to ferret out this most common cause of "essential" hypertension. This is es...
متن کاملPrimary aldosteronism in diabetic subjects with resistant hypertension: response to Umpierrez et al.
OBJECTIVE Despite the high prevalence of hypertension in patients with type 2 diabetes, the prevalence of primary aldosteronism in this population has not been determined. RESEARCH DESIGN AND METHODS One hundred subjects with type 2 diabetes and resistant hypertension, defined as blood pressure > 140/90 mmHg despite the use of > or = 3 antihypertensive agents, were screened for primary aldost...
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ژورنال
عنوان ژورنال: Journal of Hypertension
سال: 2021
ISSN: 0263-6352,1473-5598
DOI: 10.1097/01.hjh.0000748648.44959.b0